Protest action on Sunday afternoon led to the closure of parts of a Jakes Gerwel and Highlands drives in Mitchells Plain.
Residents of the Siqalo informal settlement earlier threw stones at vehicles and set tyres alight, authorities confirmed.
About 400 protesters had also burnt rubble in the road and traffic was diverted by metro police.
Police were also on the scene and after the crowd was addressed by the public order police, protesters returned to their homes, said mayoral committee member for safety and security JP Smith.
Fire services are currently cleaning the scene.
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